NFL Week 15 Predictions, Picks & Betting Odds

We have expert betting predictions for Week 15 of the 2021 NFL season, which starts with the Chiefs vs Chargers.

There are 16 games this week for punters to enjoy, so the betting opportunities are endless. We preview every game for all 18 weeks of the regular season and the playoffs.

NFL Week 15 Picks

Kansas City Chiefs vs Los Angeles Chargers @ SoFi Stadium

The Kansas City Chiefs are one of the hottest teams in the NFL and we’re supporting them against the Chargers.

They are now 9-4 after looking average to start the season, and although the Chargers are playing well, Patrick Mahomes and the Chiefs are on a different level.

Take the –3 line, which is favourable.

Betting tip: Kansas City Chiefs -3

Chiefs by 7

Las Vegas Raiders vs Cleveland Browns @ FirstEnergy Stadium

Nothing is going right for the Raiders and we couldn’t follow them for the rest of the season.

Cleveland bounced back with a nice win over Baltimore last week, and despite only narrowly holding on, they looked excellent over the first three quarters.

We’re happy to take the $2.05 for the home team despite the players on the COVID list.

Betting tip: Cleveland Browns

Browns by 7

New England Patriots vs Indianapolis Colts @ Lucas Oil Stadium

The Patriots are the better team and they are 6-0 on the road, but this is a good time to bet on the Colts.

Indianapolis is gathering momentum at 7-6 and it could make a serious run for a playoff spot with a win against New England.

Bookmakers are offering $1.71, which suggests how tough they’ll be on Sunday.

Betting tip: Indianapolis Colts

Colts by 6

Carolina Panthers vs Buffalo Bills @ Highmark Stadium

The Bills have endured some tough defeats in recent weeks, but now is their chance to shine.

They should take care of the Carolina Panthers with ease, which is why bookmakers have the line at 10.5.

It should be a comfortable victory for the home team in favourable conditions.

Betting tip: Buffalo Bills –10.5

Bills by 14

Arizona Cardinals vs Detroit Lions @ Ford Field

The Lions did well to beat Minnesota and end their winless streak, but beating Arizona is unrealistic.

The Cardinals couldn’t muster much against the Los Angeles Rams last week, but they played well enough to put up a big number on the Lions.

We don’t think 12.5 points will be nearly enough for the Lions, who will do well to keep this game within three touchdowns.

Betting tip: Arizona Cardinals –12.5

Cardinals by 18

New York Jets vs Miami Dolphins @ Hard Rock Stadium

We have more confidence in the Miami Dolphins than the Jets, so back the home team confidently.

Bookmakers agree with the Dolphins paying $1.20 to win, which is short for a 6-7 team, but they aren’t facing much in the way of opposition.

They are 4-3 at home, so take them to score a comfortable victory.

Betting tip: Miami Dolphins -10

Dolphins by 14

Dallas Cowboys vs New York Giants @ MetLife Stadium

It’s hard to know what the Dallas Cowboys will bring on a weekly basis, but they should be too good for the Giants.

Dallas comes off a strong win and Dak Prescott is still one of the best quarterbacks in the NFL. He should lead the Cowboys to an easy win over New York, which isn’t showing much energy.

The Giants are playing for a better draft pick, so we couldn’t put our hard-earned money on them.

Betting tip: Dallas Cowboys –10.5

Cowboys by 17

Washington Football Team vs Philadelphia Eagles @ Lincoln Financial Field

The confidence levels of the Eagles have soared since the quarterback change and we’re all for it.

Gardner Minshew is a much better quarterback than Jalen Hurts and the Eagles are starting to produce the goods.

Washington can be a tough bet, so take the Eagles to cover the spread at home.

Betting tip: Philadelphia Eagles –7

Eagles by 10

Tennessee Titans vs Pittsburgh Steelers @ Heinz Field

We love backing the Titans and we think they’ll show up against the Steelers on Monday morning.

They improved to 9-4 and they are showing good maturity, so we’re confident they can beat the resurgent 6-6-1 Steelers.

Bookmakers have the Titans at $1.77, which is a value price for the better team.

Betting tip: Tennessee Titans

Titans by 3

Houston Texans vs Jacksonville Jaguars @ TIAA Bank Field

Tread carefully with this bet as both teams are 2-11. We favour the Jaguars to get a win at home as they have more upside.

It has been a rough season for the Texans and Jaguars, but if the home side can’t beat Houston, heads will roll in Jacksonville.

Take the –3.5 spread, which is a fair line for this contest.

Betting tip: Jacksonville Jaguars –3.5

Jaguars by 10

Cincinnati Bengals vs Denver Broncos @ Empower Field

We haven’t been impressed with either team lately, but the Broncos could get the win at home.

They are 7-6 and still a chance to make the playoffs, so beating the Bengals would go a long way to that happening.

There won’t be much between them, so the $1.67 head-to-head price is worth including to NFL multis.

Betting tip: Denver Broncos

Broncos by 6

Atlanta Falcons vs San Francisco 49ers @ Levi’s Stadium

The Falcons haven’t been too poor this season, despite a record of 6-7. They have been in the fight, so the +9 points is fair.

San Francisco doesn’t cover big spreads very often, so this game is purely on numbers. The line favours the Falcons on the road.

Betting tip: Atlanta Falcons +9

Falcons by 3

Seattle Seahawks vs Los Angeles Rams @ SoFi Stadium

The Rams looked amazing against the Cardinals last week and a repeat performance is likely.

They dispatched one of the best teams in the NFL, so taking care of the 5-8 Seahawks shouldn’t be too difficult.

We’re not sure why they’re not at shorter odds with bookies, but we’re happy to take the value.

Betting tip: Los Angeles Rams –4.5

Rams by 10

Green Bay Packers vs Baltimore Ravens @ M&T Bank Stadium

The Packers are firing on all cylinders after producing the goods against Chicago last week.

We haven’t been impressed with what Baltimore has offered and Lamar Jackson has been wildly inconsistent.

Most of the early money has come for the Packers and with good reason.

Betting tip: Green Bay Packers –4.5

Packers by 7

New Orleans Saints vs Tampa Bay Buccaneers @ Raymond James Stadium

The Buccaneers continue to produce the goods at home after winning in overtime last week. They are now 6-0 at home and that record should stay intact.

New Orleans hasn’t been playing well enough to beat Tom Brady and the Buccaneers, so it should be a comfortable victory in front of home fans.

Take the –10.5 line, which could move throughout the week.

Betting tip: Tampa Bay Buccaneers –10.5

Buccaneers by 14

Minnesota Vikings vs Chicago Bears @ Soldier Field

A close game is expected between the Vikings and Bears, but our money is on the Vikings.

They still have a chance to make the playoffs and the Bears, despite scoring 30 points last week, could have given up the ghost.

It’s a must-win for the Vikings and they can handle the pressure.

Betting tip: Minnesota Vikings

Daryl Curnow
About the Author: Daryl Curnow

After graduating from the University of Auckland (BA – English), Daryl was thrown into the world of sports and horse racing journalism.
Having worked as a racing journalist for two years, he decided to move into the online world of horse racing and sports writing. Coupled with his love of US sport, Daryl’s picks have been featured on various websites around the world and viewed by millions of readers. After years of honing his craft, Daryl became a professional punter in 2009 – with a focus on horse racing, NBA, NFL, and college sports. When he’s not working, Daryl tries to avoid making bogeys on the golf course.